Sickle Cell Disease (SCD) is caused by a single base change, from adenine to thymine, on the HBB gene. Hemoglobin, a molecule in RBCs, is responsible for delivering oxygen to tissues throughout the body. Sickle cell hemoglobin, or hemoglobin S, forms chains in the cell, causing normal cells to sickle and become stiff. This can obstruct blood vessels and ultimately cause damage to organs. This is what causes the symptoms and complications of SCD. Recently, researchers and scientists have been conducting trials to cure the disease using gene therapy. If scientists can switch the mutated gene back to the normal gene, the symptoms will no longer occur. So far, there have been some successful cases. This is a huge breakthrough in science. Many people believe gene therapy will continue to develop and be a more effective cure in the future. This would heavily improve the quality of patients' lives and has the potential to even cure the disease. Collaboration with Dr. Umut Gurkan- Case Biomanufacturing and Microfabrication Laboratory
Sickle Cell Disease (SCD) is caused by a single base change, from adenine to thymine, on the HBB gene. Hemoglobin, a molecule in RBCs, is responsible for delivering oxygen to tissues throughout the…
12020-03-10T17:17:20+00:00Amanda Koziurad8cad79289ca6f3a766facb6fa0fbb11898df0362020 Art of STEMDaniela Solomon19Submissions from the 2020 contestgallery2024-02-02T19:19:00+00:00Daniela Solomone316041929e7cb3504341dbd1e9eb2f7bd821a14
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12020-03-10T17:17:20+00:00Amanda Koziurad8cad79289ca6f3a766facb6fa0fbb11898df0362020 Art of STEMDaniela Solomon23Submissions from the 2020 contestgallery2024-02-02T19:46:34+00:00Daniela Solomone316041929e7cb3504341dbd1e9eb2f7bd821a14
12020-03-11T17:42:30+00:00Kyle Jones061ae84fb0af3ee4257d662c0654a6ffc248e2d5Case Western Reserve University (CWRU)Amanda Koziura5Submissions from the 2020 contest by the CWRU community and other local collegesgallery2020-03-13T17:37:56+00:00Amanda Koziurad8cad79289ca6f3a766facb6fa0fbb11898df036